Dr Rachael Rigby

Lecturer in Biomedicine

Publications

Ding S, Chi MM, Scull BP, Rigby R, Schwerbrock NM, Magness S, Jobin C, Lund PK. High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PLoS One. 2010 Aug 16;5(8).

Speck KE, Garrison AP, Rigby RJ, von Allmen DC, Lund PK, Helmrath MA. Inflammation Enhances Resection-Induced Intestinal Adaptive Growth in IL-10 Null Mice. J Surg Res. 2011 168 (1) 62-69.

Rigby RJ, Hunt MR, Scull BP, Simmons JG, Speck KE, Helmrath MA, Lund PK. A new animal model of post-surgical inflammatory bowel disease and fibrosis: the effect of commensal microflora. Gut. 2009 Aug; 58(8):1104-12.

Dekaney CM, von Allmen DC, Garrison AP, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection. Surgery. 2008 Aug;144(2):174-81.

Lund PK, Rigby RJ. What are the Mechanisms of Fibrosis in IBD? Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S127-8.

RJ Rigby, JG Simmons, CJ Greenhalgh, WS Alexander and PK Lund. Suppressor of cytokine signalling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon. Oncogene, 2007 Jul 19;26(33):4833-41.

Dekaney CM, Fong JJ, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007; Nov; 293(5):G1013-22.

P.K. Lund, R.J. Rigby. SOC-ing it to tumors: Suppressors of Cytokine Signalling as Tumor Repressors. Gastroenterology, 2006. Jul; 131 (1) 317-19.

Rigby RJ, Knight SC, Kamm MA and Stagg AJ. Production of IL-10 and IL-12 by murine colonic dendritic cells in response to microbial stimuli. Clinical and Experimental Immunology, 2005. Feb; 139:245-256.

Hart AL, Al-Hassi HO, Rigby RJ, Bell SJ, Emmanuel AV, Knight SC, Kamm MA, Stagg AJ. Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Gastroenterology. 2005 Jul;129(1):50-65.

Bell SJ, Rigby RJ, English N, Mann S, Knight SC, Kamm MA and Stagg AJ. Migration and maturation of human colonic dendritic cells. Journal of Immunology, 2001. Apr; 166:4958-67.